1. Amino acids pathway
If you ingest or consume too much or more than usual of something, your body knows how to use it. Excess fat intake can cause cholesterol in sedentary individuals.
When bodybuilders doing strenuous exercises take fat, it gets converted to cholesterol and a good portion of that cholesterol gets converted to testosterone, which they require for working out in the gym. All in all, the human body does a pretty good job of assessing what reason or purpose the compounds are to be used for.
AS we know, hGH is a peptide hormone comprising of several amino acids. So, when we consume lots of amino acids, we are giving the body a signal to produce more of hGH. Amino acids like L-Arginine, L-Ornithine, L-Lysine, L-Tyrosine, L-Glutamine, L-Glycine, L-Valine all give this signal to the body.
That is the reason why intravenous injections of amino acids were documented to increase human growth hormone dramatically.
Experts believe that amino acids intake signals the body to produce more GHRH (growth hormone releasing hormone) which in turn signals the pituitary to produce more hGH.
However, every action has an equal and opposite reaction. This is what the homeostasis system of the body is supposed to do, it tries to maintain the same hormonal levels in the body.
So, when you take in all those amino acids, the body will try its best to counter the effects so that the change in hGH levels does not happen. That is the reason why after few days of those amino acids injections, the growth hormone levels in the subjects returned to normal levels.
Scientists are still researching on the exact mechanisms of the “homeostasis” which tries to keep the same levels of the hormones in the body, however here are some well established mechanisms:-
i. After a surge in growth hormone levels, the human body produces “somatostatin”, a hormone that signals the pituitary gland to stop producing more growth hormone.
ii. When the human body takes excess amino acids, somatostatin also signals the “intestines” to stop absorption of amino acids. However, “somatostatin” action can be blocked by using other ingredients that work via cholinergic pathway.
So, you see everything has a catch. That’s why you need a multi-ingredient HGH supplement that works on different pathways to bring about a comprehensive effect.